| PUBLICATIONS IN INTERNATIONAL REFEREED JOURNALS WITH IMPACT FACTOR
75) “Chromatographic behavior of the biologically active proline derivative captopril on particulate, monolithic and core-shell narrow bore columns” C.K. Zacharis, T.D. Karakosta, P.D. Tzanavaras*, P. Rigas and D.G. Themelis Anal. Meth., 4 (2012) 4373
74) “High-throughput
determination of quinine in beverages and soft drinks based on
zone-fluidics coupled to monolithic liquid chromatography” P.D. Tzanavaras*, C.K. Zacharis, T.D. Karakosta, A. Zotou and D.G. Themelis Anal. Lett., in press.
73) “Isocratic
liquid chromatographic determination of three paraben preservatives in
hygiene wipes using a reversed phase core-shell narrow-bore column” P.D. Tzanavaras*, T.D. Karakosta, P.G. Rigas, D.G. Themelis and A. Zotou Centr. Eur. J. Chem., 10 (2012) 1459
72) “On-line
micro-volume introduction system developed for lower density than water
extraction solvent and dispersive liquid-liquid microextraction coupled
with flame atomic absorption spectrometry” A. Anthemidis*, C. Mitani, P. Balkatzopoulou and P.D. Tzanavaras Anal. Chim. Acta, 733 (2012) 34
71) “Automated
determination of total captopril in urine by liquid chromatography with
post-column derivatization coupled to on-line solid phase extraction in
a sequential injection manifold” T.D. Karakosta, P.D. Tzanavaras and D.G. Themelis* Talanta, 88 (2012) 561
70) “Automated
determination of hydrogen peroxide at the micro-molar level in
rainwater and snow using a stopped-flow approach in a hybrid sequential
injection/flow injection manifold” P.D. Tzanavaras* and E. Boulimari Anal. Lett., 45 (2012) 1086
69) “On-line
cleavage of disulfide bonds by soluble and immobilized
tris-(2-carboxyethyl)phosphine using sequential injection analysis” P.D. Tzanavaras*, C. Mitani, A. Anthemidis and D.G. Themelis Talanta, 96 (2012) 21
68) “A green HPLC method for the determination of N-acetylcysteine using post-column derivatization with methyl-propiolate” P.D. Tzanavaras* Instrum. Sci. & Technol., 40 (2012) 150
67) “Automated
derivatization of pharmaceutically active thiols under flow conditions
using an o-phthalaldehyde / glycine fluorogenic system and sequential
injection analysis.” T.D. Karakosta and P.D. Tzanavaras* Anal. Lett., 44 (2011) 2530
66) “Automated
pre-column derivatization of thiolic fruit-antibrowning agents by
sequential injection coupled to high performance liquid chromatography
using a monolithic stationary phase and an in-loop stopped-flow
approach” T.D. Karakosta, P.D. Tzanavaras and D.G. Themelis* J. Sep. Sci., 34 (2011) 2240
65) “Development
and validation of an ultra-fast liquid chromatographic method for the
quality control of famotidine formulations using a short monolithic
stationary phase.” P.D. Tzanavaras* Central Eur. J. Chem., 9 (2011) 446
64) “Development
and validation of a rapid HPLC method for the determination of five
banned fat-soluble colorants in spices using a narrow-bore monolithic
column.” C.K. Zacharis*, F.S. Kika, P.D. Tzanavaras, P. Rigas and E.R. Kyranas Talanta, 84 (2011) 480 63) “Ethyl
propiolate as a post-column derivatization reagent for thiols:
development of a green liquid chromatographic method for the
determination of glutathione in vegetables.” C.K. Zacharis, P.D. Tzanavaras* and A. Zotou Anal. Chim. Acta, 690 (2011) 122
62) “HPLC
separation of nimesulide and five impurities using a narrow-bore
monolithic column: application to photo-degradation studies.” C.K. Zacharis and P.D. Tzanavaras* Chromatographia, 73 (2011) 347
61) “Automated tagging of pharmaceutically active thiols under flow conditions using monobromobimane.” P.D. Tzanavaras* and T.D. Karakosta J. Pharm. Biomed. Anal., 54 (2011) 882
60) “NBD-Cl as a post-column reagent for primary and secondary amines after separation by ion-exchange chromatography.” C.K. Zacharis, P.D. Tzanavaras, P.N. Mouroutis and P. Rigas* Anal. Lett., 44 (2011) 1821
59) “Automated determination of Captopril by flow and sequential injection analysis: a review” P.D. Tzanavaras* Anal. Lett., 44 (2011) 560
58) “Derivatization of thiols under flow conditions using two commercially available propiolate esters.” P.D. Tzanavaras*, A. Tsiomlektsis and C.K. Zacharis J. Pharm. Biomed. Anal., 53 (2010) 790
57) “LC-determination
of five paraben preservatives in saliva and toothpaste samples using UV
detection and a short monolithic column.” A. Zotou*, I. Sakla and P.D. Tzanavaras J. Pharm. Biomed. Anal., 53 (2010) 785
56) “Solvent-based
de-emulsification dispersive liquid-liquid microextraction combined
with gas chromatography – mass spectrometry for determination of trace
organochlorine pesticides in environmental water samples.” C.K. Zacharis*, P.D. Tzanavaras, C. Roubos, K. Dima J. Chromatogr. A, 1217 (2010) 5896
55) “On-line
derivatization of N-acetylcysteine using ethyl-propiolate as a novel
advantageous reagent and sequential injection analysis”. P.D. Tzanavaras*, C.K. Zacharis and D.G. Themelis Anal. Lett., 43 (2010) 1889
54) “High throughput automated determination of glutathione based on the formation of a UV-absorbing thioacrylate derivative” (Invited article) C.K. Zacharis and P.D. Tzanavaras* Comb. Chem. & High Through. Screen., 13 (2010) 461
53) “Recent advances in the analysis of organic impurities of active pharmaceutical ingredients and formulations: a review” P.D. Tzanavaras* Curr. Org. Chem., 14 (2010) 2348
52) “Rapid
determination of methylxanthines in real samples by high performance
liquid chromatography using the new FastGradientŪ narrow-bore
monolithic column.” P.D. Tzanavaras*, C.K. Zacharis and D.G. Themelis Talanta, 81 (2010) 1494
51) “Generic
automated fluorimetric assay for the quality control of gamma
aminobutyric acid-analogue anti-epileptic drugs using sequential
injection analysis”. D.G. Themelis*, P.D. Tzanavaras and E.A. Boulimari Anal. Lett., 43 (2010) 905
50) “Ethyl-propiolate
as a novel and promising analytical reagent for the derivatization of
thiols: study of the reaction under flow conditions.” C.K. Zacharis*, P.D. Tzanavaras and D.G. Themelis J. Pharm. Biomed. Anal., 50 (2009) 384
49) “Automated
zone-sampling dilution by coupling sequential injection analysis to
high-throughput HPLC for the direct determination of gemfibrozil.” P.D. Tzanavaras*, D.G. Themelis and P. Rigas J. Sep. Sci., 32 (2009) 2819
48) “Automated
sample preparation coupled to sequential injection chromatography:
on-line filtration and dilution protocols prior to separation.” C.K. Zacharis, A. Verdoukas, P.D. Tzanavaras* and D.G. Themelis J. Pharm. Biomed. Anal., 49 (2009) 726
47) “Development
and validation of a micellar electrokinetic chromatography method for
the purity control of nimesulide pharmaceuticals.” C.K. Zacharis, P.D. Tzanavaras*, M. Notou, A. Zotou and D.G. Themelis J. Pharm. Biomed. Anal., 49 (2009) 201
46) “Selective
determination of cyanides by gas diffusion – stopped flow – sequential
injection analysis and an on-line standard addition approach.” D.G. Themelis*, S. Karastogianni and P.D. Tzanavaras Anal. Chim. Acta, 632 (2009) 93
45) “Hybrid
sequential injection – flow injection manifold for the
spectrophotometric determination of total sulfite in wines using
o-pthalaldehyde and gas-diffusion.” P.D. Tzanavaras, E. Thiakouli and D.G. Themelis* Talanta, 77 (2009) 1614
44) “Amperometric
determination of cyanides at the low ppb level by automated
preconcentration based on gas diffusion coupled to sequential injection
analysis.” C.K. Zacharis*, P.D. Tzanavaras, A.N. Voulgaropoulos* and B. Karlberg Talanta, 77 (2009) 1620
43) “Novel
automated assay for the quality control of mexiletine hydrochloride
formulations using sequential injection and on-line dilution.” P.D. Tzanavaras*, C.K. Zacharis and P. Rigas J. Pharm. Biomed. Anal., 48 (2008) 1254
42) “Determination
of bisphosphonate active pharmaceutical ingredients in pharmaceuticals
and biological material: A review of analytical methods.” C.K. Zacharis* and P.D. Tzanavaras J. Pharm. Biomed. Anal., 48 (2008) 483
41) “Extraction
of acyclovir from pharmaceutical creams prior to HPLC assay analysis.
Optimization and validation of pre-treatment protocols.” (invited
article) P.D. Tzanavaras and C.K. Zacharis* Central Eur. J. Chem., 6 (2008) 140
40) “Optimization
and validation of a dissolution test for selegiline hydrochloride
tablets by a novel rapid HPLC assay using a monolithic stationary
phase.” P.D. Tzanavaras*, D.G. Themelis, A. Zotou, J. Stratis and B. Karlberg J. Pharm. Biomed. Anal., 46 (2008) 670
39) “Sequential-injection analysis: a useful tool for clinical and biochemical analysis.” (invited article) A. Economou*, P.D. Tzanavaras and D.G. Themelis Curr. Pharm. Anal., 3 (2007) 249
38) “Review of recent applications of flow injection spectrophotometry to pharmaceutical analysis.” P.D. Tzanavaras* and D.G. Themelis Anal. Chim. Acta, 588 (2007) 1
37) “Automated
determination of flutamide by a validated flow-injection method.
Application to dissolution studies of pharmaceutical tablets.” P.D. Tzanavaras* and D.G. Themelis J. Pharm. Biomed. Anal., 43 (2007) 1820
36) “Highly
selective flow injection spectrophotometric determination of gold based
on its catalytic effect on the oxidation of variamine blue by potassium
iodate in aqueous N,N-dimethylformamide medium” D.G. Themelis*, A.V. Trellopoulos, P.D. Tzanavaras and M. Sofoniou Talanta, 72 (2007) 277 35) “Review on analytical methods for the determination of chlorine dioxide” (invited article) P.D. Tzanavaras*, D.G. Themelis* and F.S. Kika Central Eur. J. Chem., 5 (2007) 1
34) “Rapid
HPLC assay of acyclovir and its major impurity guanine in raw materials
and pharmaceutical creams using a monolithic column and a flow gradient
approach” P.D. Tzanavaras* and D.G. Themelis J. Pharm. Biomed. Anal., 43 (2007) 1526
33) “Validated high-throughput HPLC assay for nimesulide using a short monolithic column” P.D. Tzanavaras* and D.G. Themelis J. Pharm. Biomed. Anal., 43 (2007) 1483 32) “Development
and validation of a high-throughput HPLC assay for the determination of
caffeine in food samples using a monolithic column” P.D. Tzanavaras* and D.G. Themelis Anal. Chim. Acta, 581 (2007) 89
31) “Optimization and validation of a dissolution test for famotidine tablets using flow injection analysis” P.D. Tzanavaras*, A. Verdoukas and T. Balloma J. Pharm. Biomed. Anal., 41 (2006) 437
30) “Sequential Injection Analysis : Principles, Construction of a SIA Analyzer and Demonstration by a Simple Experiment” A. Economou*, P.D. Tzanavaras and D.G. Themelis J. Chem. Educ., 82 (2005) 1820
29) “Development
and validation of a flow injection assay for the dissolution studies of
the anti-depressant drug venlafaxine.” P.D. Tzanavaras*, A. Verdoukas and D.G. Themelis Anal. Sci., 21 (2005) 1515
28) “Validated flow injection spectrophotometric assay for the quality and stability control of gemfibrozil tablets.” P.D. Tzanavaras* and D.G. Themelis Anal. Lett., 38 (2005) 2165
27) “Assay of the synthetic estrogen fosfestrol in pharmaceutical formulations using capillary electrophoresis.” D.G. Themelis*, A.V. Trelopoulos, P.D. Tzanavaras and B. Karlberg J. Pharm. Biomed. Anal., 39 (2005) 559
26) “Normal
spectrophotometric and stopped-flow spectrofluorimetric sequential
injection methods for the determination of alendronic acid, an
anti-osteoporosis amino-bisphosphonate drug.” P.D. Tzanavaras, C.K. Zacharis, G. Theodoridis*, Ε.Α. Kalaitzantonakis and A. Voulgaropoulos Anal. Chim. Acta, 547 (2005) 98
25) “Determination
of orthophosphate in urine by sequential injection analysis with
on-line dilution and photometric detection.” D.G. Themelis*, A. Economou, A. Tsiomlektsis and P.D. Tzanavaras Anal. Biochem., 330 (2004) 193
24) “Rapid spectrofluorimetric determination of lisinopril in pharmaceutical tablets using sequential injection analysis.” C.K. Zacharis, P.D. Tzanavaras, D.G. Themelis*, G. Theodoridis, A. Economou, P. Rigas Anal. Bioanal. Chem., 379 (2004) 759 23) “Determination of boron in water and pharmaceuticals by sequential injection analysis and fluorimetric detection.” A. Economou*, D.G. Themelis, H. Bikou, P.D. Tzanavaras and P.G. Rigas Anal. Chim. Acta, 510 (2004) 219 22) “Automated
sample preparation based on the sequential injection principle. Solid –
phase extraction on a molecularly imprinted polymer coupled on-line to
high-performance liquid chromatography.” G. Theodoridis*, C.K. Zacharis, P.D. Tzanavaras, D.G. Themelis and A. Economou J. Chromatogr. A, 1030 (2004) 69
21) “Determination
of carbimazole and methimazole in pharmaceuticals by flow injection
with chemiluminescence detection based on the inhibition of the
Cu(II)-catalyzed luminol-hydrogen peroxide reaction.” A. Economou*, P.D. Tzanavaras, M. Notou and D.G. Themelis. Anal. Chim. Acta, 505 (2004) 129
20) “Sequential injection method for the direct spectrophotometric determination of bismuth in pharmaceutical products.” P.D. Tzanavaras, D.G. Themelis* and A. Economou. Anal. Chim. Acta, 505 (2004) 167 19) “Novel
flow-injection spectrophotometric determination of fosinopril using
UV-assisted digestion and an orthophosphates calibration graph.” P.D. Tzanavaras and D.G. Themelis*. Anal. Chim. Acta, 481 (2003) 321
18) “Flow
injection manifold for the rapid spectrophotometric determination of
fosfestrol, following on-line thermal induced digestion by
peroxodisulfate ion and using an orthophosphate calibration graph.” P.D. Tzanavaras and D.G. Themelis* Talanta, 59 (2003) 207
17) “Flow
and sequential injection manifolds for the spectrophotometric
determination of captopril based on its oxidation by Fe(III).” P.D. Tzanavaras, D.G. Themelis*, A. Economou and G. Theodoridis. Μicrochim. Acta, 142 (2003) 55
16) “Sensitive
determination of captopril by flow injection analysis with
chemiluminescence detection based on the enhancement of the luminol
reaction.” A. Economou*, D.G. Themelis, G. Theodoridis and P.D. Tzanavaras. Anal. Chim. Acta, 463 (2002) 249
15) “Rapid
spectrophotometric determination of fosfestrol following on-line
hydrolysis by alkaline phosphatase using flow injection and chasing
zones.” P.D. Tzanavaras, D.G. Themelis* and B. Karlberg. Anal. Chim. Acta, 462 (2002) 119
14) “Flow-injection
spectrophotometric determination of the antibiotic fosfomycin in
pharmaceutical products and urine samples after on-line thermal induced
digestion.” P.D. Tzanavaras and D.G. Themelis*. Anal. Biochem., 304 (2002) 244
13) “Reversed
flow-injection manifold for the spectrophotometric determination of
captopril based on its inhibitory effect on the Co(II)-
2,2΄-dipyridyl-2-pyridylhydrazone complex formation.” P.D. Tzanavaras, D.G. Themelis*, A. Economou and G. Theodoridis. Talanta, 57 (2002) 575
12) “Simultaneous
flow-injection determination of fluoride, monofluorophosphate and
orthophosphate ions using alkaline phosphatase immobilized on a
cellulose nitrate membrane and an open-circulation approach.” P.D. Tzanavaras and D.G. Themelis*. Anal. Chim. Acta, 467 (2002) 83
11) “Solvent
extraction flow-injection manifold for the simultaneous
spectrophotometric determination of free cyanide and thiocyanate ions
based upon on-line masking of cyanides by formaldehyde.” (Part of PhD
Thesis) D.G. Themelis* and P.D. Tzanavaras. Anal. Chim. Acta, 452 (2002) 295
10) “Direct
and selective flow-injection method for the simultaneous
spectrophotometric determination of calcium and magnesium in red and
white wines using on-line dilution based on “zone sampling”.” D.G. Themelis*, P.D. Tzanavaras, A. V. Trellopoulos and M.C. Sofoniou. J. Agric. Food Chem., 49 (2001) 5152
9) “Rapid
flow-injection spectrophotometric determination of monofluorophosphates
in toothpastes after on-line hydrolysis by alkaline phosphatase
immobilized on a cellulose nitrate membrane.” (Part of PhD thesis) P.D. Tzanavaras and D.G. Themelis*. Analyst, 126 (2001) 1608
8) “Flow
injection manifold for the simultaneous spectrophotometric
determination of Fe(II) and Fe(III) using
2,2΄-dipyridyl-2-pyridylhydrazone and a single-line double injection
approach.” D.G. Themelis*, P.D. Tzanavaras, F.S. Kika and M.C. Sofoniou. Fresenius’ J. Anal. Chem., 371 (2001) 364
7) “On-line
dilution flow injection manifold for the selective spectrophotometric
determination of ascorbic acid based on the iron(II)- 2,
2-dipyridyl-2-pyridyl hydrazone complex formation.” D.G. Themelis*, P.D. Tzanavaras and F.S. Kika. Talanta, 55 (2001) 127
6) “Simple, rapid reagent-injection spectrophotometric determination of fluorides in pharmaceutical formulations.” D.G. Themelis*, P.D. Tzanavaras and H.D. Tzanavaras. J. Pharm. Biomed. Anal., 25 (2001) 971
5) “Flow
injection manifold for the direct spectrophotometric determination of
bismuth in pharmaceutical products using methylthymol blue as colour
forming agent.” D.G. Themelis*, P.D. Tzanavaras and J.K. Papadimitriou. Analyst, 126 (2001) 247
4) “Simultaneous
spectrophotometric determination of fluoride and monofluorophosphate
ions in toothpastes using a reagent-injection manifold.” (Part of PhD
Thesis) D.G. Themelis* and P.D. Tzanavaras. Anal. Chim. Acta, 429 (2001) 113
3) “Reagent-injection
spectrophotometric determination of citric acid in beverages and
pharmaceutical formulations based on its inhibitory effect on the
iron(III) catalytic oxidation of 2, 4-diaminophenol by hydrogen
peroxide.” (Part of PhD Thesis) D.G. Themelis* and P.D. Tzanavaras. Anal. Chim. Acta, 428 (2001) 23
2) “Normal
and differential demasking flow injection manifold for the direct
spectrophotometric deterimnation of zinc(II) in biological materials
and pharmaceutical formulations.” D.G. Themelis*, P.D. Tzanavaras, A.A. Liakou, H.D. Tzanavaras and J.K. Papadimitriou. Analyst, 125 (2000) 2106
1) “Direct,
selective flow injection spectrophotometric determination of calcium in
wines using methylthymol blue and an on-line cascade dilution system.” D.G. Themelis*, P.D. Tzanavaras, A.N. Anthemidis and J. Stratis. Anal. Chim. Acta, 402 (1999) 259
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